Parkinson’s Disease Symptoms and Treatment

What is Parkinson’s Disease?

Parkinson’s disease (also known as Parkinson disease, Parkinson’s, idiopathic parkinsonism, primary parkinsonism, PD or paralysis agitans) is a progressive debilitating neurodegenerative disorder of the motor system. The disease results in the loss of the neurons or nerve cells that contain dopamine in the substantia niera, the part of the brain that controls movement.

What causes Parkinson’s disease?

The cause is unknown though several factors are considered to be linked to the development of the disease. Approximately 15% of sufferers have a family history of the disease, but it has not been proven whether this is due to genetic or environmental factors. One theory is that environmental factors such as toxins play a part in the neurons ability to produce dopamine. Other theories focus on the neurons dying due to the aging process or because of exposure to free radicals. Though the causes of the disease have not been proven, the following factors increase the risk of Parkinson’s;

* Age
* Male
* Genetic link to a sufferer
* Stress
* Head trauma
* Environmental exposure to pesticides
* Rural living
* High fat diet

There are also three factors that have been associated with a decreased risk of Parkinson’s, these are cigarette smoking, anti-oxidants being present in diet and having measles early in life.

Parkinson’s disease Symptoms

Motor symptoms are the primary symptom, with tremors starting in one area (e.g. a hand or leg) and then developing in other parts of the body. However, not all tremors are due to Parkinson’s disease. Stiffness and slowness in movements are also symptoms of the disease and can cause cramps and soreness. Sufferers may develop issues with walking imbalance, feet shuffling and stooped posture. Parkinson’s disease may also cause swallowing difficulties and gastrointestinal problems such as constipation and incontinence. The disease may inhibit brain function and cause dementia. Sufferers may also experience fatigue, depression and emotional changes.

Comparing Online Travel Services To Your Local Travel Agent

Sites such as Expedia, Orbitz, and Travelocity claim to offer the best price – sometimes even guaranteed. They may even claim to offer the best rates on a luxury world cruise, a trip that travel wholesalers publicly prefer to be sold by agents. The emergence of online travel sites have put many agencies out of business, and claim to have conquered the consumer base by offering quality product at a lower cost. When you call your local travel agency and ask for a price quote on an air and hotel luxury travel vacation package, most consumers will check against one of the more popular travel websites to see what prices better. True, two thirds of the time, you will find that the Internet will beat the travel agent price by about $150. The travel website will assure you that it is the same package. The resorts and hotels are aware that you are going to be in the most unfavorable rooms, in fact, that is why they sold them to the Internet travel site at a discounted rate in the first place.

Travel service sites proudly proclaim that they are able to further save customers money by selling large volumes of travel and collecting a smaller fee. Orbitz and Travelocity do have a large volume of travel reservations made, but what little they make in commission they make back in changed or canceled reservations. Most travel agencies offer a travel insurance that covers you and your travel companions if you should have to cancel for a medical or personal emergency.

American Express Travel offers a cancel for any reason insurance that even covers your airline tickets. These Internet booking engines are now beginning to offer “insurance,” but it rarely covers cancellations in full. Your local travel agent is there to offer the customer care you need back at home while you’re traveling abroad. When it comes to planning luxury travel vacation, you are truly better off using a travel agent. If you don’t like your room, your travel agent can have it fixed in a matter of moments. Travel agents are not focused on quantity, but quality. So travel safe, not sorry, and call a travel agent to hear more benefits that each agency offers their clients

Machine Tool Industry Quietly Recovery

By lower automobile, engineering machinery, electrical equipment and aerospace industry product demand pull, the machine tool industry is experiencing accelerated warming trend. China Securities Journal reporter learned that, at present, a lot of construction machinery and equipment category Power Grid Company is intensity of technological transformation, have added special milling large heavy equipment. Required for the development of large aircraft aluminum alloy high-speed cutting machines and cutting machines are also difficult to process materials as in hot demand.

Affected by this machine plate Qinchuan development companies such as Shenyang Machine Tool orders currently in hand more than the guaranteed performance.

Warmer downstream demand driving machine

Secondary market, the development of the recent gains Qinchuan obvious, from the end of March the upside to the current 11 yuan to 14 yuan, up 27.2% gain in 10 trading days.

Shenyang Machine Tool were up in 10 days or more than 30%.

Qinchuan Development Office, said the person, company orders full. This year will further expand the field of grinding in the car market share, while increasing the sales force composite machining center, there are some new products will be introduced. In addition, the company will also increase with the machine tool manufacturing-related services-based business development. These are the company’s new profit growth point.

Qinchuan development report shows that the top ten shareholders of circulation share of seats all the institutions, there are two combinations of social security.

Number of Shareholders by the end of the third quarter, 4.82 million shares plunged to the end of 33400, chips concentration was evident. Shenyang Machine Tool very high proportion of institutional ownership, the first quarter of this year, four new entrants, including Social Security Fund 102 Portfolio, the oil companies and two pension funds.

Shenyang Machine Tool a quarterly show, the first quarter the company achieved sales revenues of 1.958 billion yuan, up 69.94%; 30.27 million yuan net profit attributable to parent company, equivalent to earnings per share were 0.06 yuan, a year earlier loss of 0.05 yuan per share, results of reverse significant.

Shenyang Machine Tool recently also adopted Placements, the company developed to the issuance of not more than 2 billion shares, and fund-raising not more than 2.1525 billion yuan for the construction of a major base of CNC machine tools, CNC lathes New CAK technical innovation, the core features of NC machine tools technological transformation and the return of bank loans for four projects.

CNC machine tools worth the wait

Lower demand in the machine tool industry, automotive and construction machinery accounted for more than 50%, military, and aerospace are also accounted for about 20%. In addition, large power grid devices also need various types of heavy machine tools. It is learned that heavy demand for machine tools rose sharply, especially in heavy-duty CNC milling machine, boring bar diameter of 250mm above floor large CNC boring and milling machine, CNC machining diameter and 16m heavy duty vertical lathes, machining diameter of 4m-5m, 14m-18m length processing CNC heavy duty horizontal lathe and CNC blade root slot milling machine so special.

As the demand for downstream production and marketing industry, strong, machine tool sales in 2010 are expected to well, especially in CNC machine tools with high added value is more worth the wait.

January-February 2010, China’s production and export of CNC machine tools were improved: total exports of metal working machines 272.767 million U.S. dollars, an increase of 14.8%; CNC machine tool exports of 6,161,700 U.S. dollars total, an increase of 32.37%. The first quarter of this year, the Shenyang Machine Tool new order contract 2.6 billion, up 100%, maintained since the February 2009 monthly growth trend.